Thursday, December 01, 2005

Comment of the Week

We are lucky enough to have La Wade, a real live scientist, saying smartypants things in the comments.

"You're right that being fat doesn't cause diabetes, but a lot of the physiological changes associated with being fat do. Fat tissue secretes a number of hormones that are important for regulation of glucose homeostasis, especially PPAR-gamma and leptin. The more fat tissue you have, the harder it is for your body to correctly regulate levels of these hormones. In addition, many overweight and obese people become so through poor diet, overeating, and lack of exercise, all of which can contribute to diabetes. You are not guaranteed to become diabetic if you're obese, but it dramatically increases your risk."

To read the rest of the comment, look here.

10 Comments:

rica said...

Dramatically increases the risk, or is dramatically corellated with increased incidence.

2:05 PM  
Jen said...

Both, rica. As I explained in my comment, the mechanism by which obesity contributes to diabetes is increasingly well understood. The good part is that correspondingly, in most patients, a weight loss of 10-15% of body mass is sufficient to significantly decrease type II diabetes symptoms.

5:25 AM  
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